Cyclooxygenase-2相关论文
Co-nanoencapsulated meloxicam and curcumin rimproves cognitive impairment induced byr amyloid-beta t
Alzheimer\'s disease is a progressive brain disorder and complex mechanisms are involved in the physiopathology of Alz......
New flavonoids and methylchromone isolated from the aerial parts of Baeckea frutescens and their inh
In the present study, we carried out a phytochemical investigation of the ethanol extract of the aerial parts of Baeckea......
We aimed to establish a novel rat model of seminal vesiculitis that would provide an effective approach to investigate t......
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Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lova
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CCL2 actives the COX-2/PGE2 pathway to accelerate the tumorgenesis of colorectal cancer via FoxO1 de
Objective CCL2(Chemokine ligand-2)is a multifunctional factor,by acting via its receptor CCR2(chemokine receptor 2)which......
The mechanisms of prostaglandin E2 involved in lipopolysaccharide-induced fever in rat lateral parab
Prostaglandin E2(PGE2)is well established as a central effector of pyrogen fever,which is synthetized by the cyclooxygen......
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Discovery of diaryl-1,2,4-triazoles bearing caffeic acid analogs as dual inhibitors of cyclooxygenas
Studies regarding the relationship between AA metabolic process and carcinogenesis revealed the novel molecular target f......
CYCLOOXYGENASE-2 INHIBITOR NS398 ENHANCES ANTI-TUMOR EFFECT OF RADIOTHERAPY IN HUMAN ANDROGEN-REFRAC
Purpose: This study was designed to examine the potential therapeutic effect ofNS398,a selective cyclooxygenase-2 (COX-2......
Although radiation-induced non-targeted responses, in vitro and in vivo, have been well studied in the past two decades,......
Benzalkonium chloride induces subconjunctival fibrosis through the COX-2-modulated activation of a T
PURPOSE The purpose is to investigate the mechanism of subconjunctival fibrosis caused by benzalkonium chloride (BAC),wh......
Inhibitory Role of the Endoplasmic Reticulum-Retained Anti-Cyclooxygenase-2 Intrabody in Hepatocellu
Hepatocellular carcinoma (HCC) has become the second leading cause of cancer death worldwide.There is a compelling need ......
THE ACTIVATIONS OF COX-2/5-LO PATHWAYS IN BRAIN AFTER FOCAL CEREBRAL ISCHEMIA-REPERFUSION INJURY AND
OBJECTIVE: To investigate the activations cyclooxygenase-2 (COX-2)/5-1ipoxygenase (5-LO) pathways of arachidonic acid (A......
The Inhibitory effect of celecoxib on Lewis lung carcinoma cell line by regulation of cyclooxygenase
Aim: Celecoxib is a potent nonsteroid anti-inflammatory drug (NSAID) that has demonstrated great promise in cancer chemo......
Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signa
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Effets of JianpiJieduRecipeonReversion of P-glycoprotein-mediated Multidrug Resistance through COX-2
To evaluate the underlying mechanism of JianpiJiedu Recipe(健脾解毒方, JJR) in the reversion of multidrug resistance con......
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Tongxinluo Inhibits Cyclooxygenase-2, Inducible Nitric Oxide Synthase, Hypoxia-inducible Factor-2α/V
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Theanine improves the function of dendritic cells via the downregulation of cyclooxygenase-2 express
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BACKGROUND Pelvic lipomatosis(PL)is a rare benign condition with characteristic overgrowth of histologically benign fat ......
Objective:Explore the role of Th1/Th2 balance in the pathogenesis of primary dysmenorrhea through study the effect of Th......
目的探讨脑胶质瘤微环境及环氧化酶2抑制剂塞来昔布对树突状细胞(dendritic cell，DC)表型和功能的影响。方法检测塞来昔布对C6细胞C......
Neuronal apoptosis and inflammatory reaction in rat models of focal cerebral ischemia following 40-m
The treatment duration of heat-sensitive moxibustion (approximately 40 minutes on average) is longer than that of tradit......
Sequential expression of cyclooxygenase-2, glutamate receptor-2, and platelet activating factor rece
Traumatic brain injury causes gene expression changes in different brain regions. Occurrence and development of traumati......
Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better tha
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To evaluate cyclooxygenase-2 (COX-2) expression induced by insulin in cultured rat vascularmuscle smooth cells (VSMCs). ......
Hepatic stellate cells(HSCs) are a kind of adipocytes. In HSCs lipids mainly exist in the form of lipid droplets. They a......
AIM: To investigate the relation between the expression of cyclooxygenase-2 (COX-2) and liver cancer, to construct the r......
Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cy
AIM: To examine whether lysophosphatidic acid (LPA)induces phosphorylation of c-Met and epidermal growth factor receptor......
AIM: To investigate the expression of cyclooxygenase-2(COX-2) in gastric cancer and its relation with the liver metastas......
AIM: Recent studies suggested that cyclooxygenase-2(COX-2) enhances tumor angiogenesis via upregulationof vascular endot......
AIM: To clarify the clinicopathologic significance of COX-2expression in human colorectal cancer.METHODS: A total of 128......
AIM: To explore the possible mechanisms of curcumin in rat colitis induced by trinitrobenzene sulfonic (TNBS) acid.rnMET......
Cyclooxygenase-2 expression after preoperative chemoradiotherapy correlates with more frequent esoph
AIM: To investigate the relationship between cyclooxygenase-2 (COX-2), and vascular endothelial growth factor (VEGF), an......
Inhibitory effect of interferon-α-2b on expression of cyclooxygenase-2 and vascular endothelial grow
AIM: TO evaluate the effects of interferon-α-2b (IFN-α-2b) on expression of cyclooxygenase-2 (COX-2) and vascular endo......
Short-term Celecoxib intervention is a safe and effective chemopreventive for gastric carcinogenesis
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AIM: To determine the possible modulating effect of the COX-2 polymorphisms, -765G→C and -1195A→G ,on the risk of colo......
AIM: To investigate the association of variations in the cyclooxygenase-2 (COX2) and uridine diphosphate glucuronosyltra......
Downregulation of p38 MAPK Involved in Inhibition of LDL-induced Proliferation of Mesangial Cells an
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Cyclooxygenase-2 Blockade Inhibits Accumulation and Function of Myeloid-derived Suppressor Cells and
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A Phase II Clinical Trial of Celecoxib Combined with Platinum-Based Regimen as First-Line Chemothera
Objective: To evaluate the efficacy and safety of celecoxib plus platinum-doublet as first-line chemotherapy in treatmen......
Effect of Th1/Th2 balance on serum prostaglandin, COX-2, AVP and OT in primary dysmenorrhea rats wit
Objective: Explore the role of Th1/Th2 balance in the pathogenesis of primary dysmenorrhea through study the effect of T......
